Resumen de la plática
Erythrocytes are specialized cells that carry haemoglobin throughout the bloodstream in all vertebrates. Obtention of mature erythrocytes involves genome-wide chromatin compaction, gain of heterochromatin, and gene silencing, making the erythroid genome a unique scenario to investigate chromatin architecture and the epigenetic mechanisms behind gene silencing. In this talk, I will show our findings exploring the molecular mechanisms behind gene silencing and their impact on erythrocyte chromatin architecture.
Mayra Furlan. Departamento de Genética Molecular, Instituto De Fisiología Celular, UNAM MX