Frontiers in Genomics: Raquel Cuevas Díaz Durán
Integrative multi-omics approaches for studying neurodegenerative diseases

Raquel Cuevas Díaz Durán. Escuela de Medicina y Ciencias de la Salud, ITESM, MX

Resumen de la plática
Neurodegenerative diseases are complex and devastating disorders characterized by the progressive degeneration of specific cell subtypes of the nervous system. They are complex, multifactorial, and heterogeneous, posing significant challenges for both understanding their underlying mechanisms and developing effective treatments. By integrating diverse omics datasets, including genomics, epigenomics, transcriptomics, genetics, and others, we aim to identify the regulatory networks driving disease progression and to identify potential biomarkers and therapeutic targets. In this seminar I will describe the multi-omics approaches we are using for the discovery of diagnostic and prognostic biomarkers in a Mexican cohort of patients with Amyotrophic Lateral Sclerosis and for understanding the regulatory mechanisms driving in vitro dopaminergic neuron differentiation.

https://research.tec.mx/vivo-tec/display/PID_66289

Frontiers in Genomics