Summary:
Human microbiomes are remarkably person specific. In the skin microbiome, individuals have similar species, yet each person has a unique consortia of strains. How these unique consortia form and persist remains a fundamental open question. To understand the assembly of these complex communities, the Lieberman Lab reconstructs the recent on-person evolution of strains on individual people, using a high-resolution, culture-based approach. In this talk, I’ll share what we’ve learned about the rules governing microbial colonization by following mutations as they arise in real time. These findings offer new perspectives on both fundamental questions in microbial ecology and the practical challenge of engineering microbiomes to improve human health.
Tami Lieberman, Massachusetts Institute of Technology, USA