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Frontiers in Genomics: Tami Lieberman
Using on-person mutation to study strain coexistence and competition in skin microbiomes
Frontiers in Genomics: Tami Lieberman
Using on-person mutation to study strain coexistence and competition in skin microbiomes
Summary: Human microbiomes are remarkably person specific. In the skin microbiome, individuals have similar species, yet each person has a unique consortia of strains. How these unique consortia form and persist remains a fundamental open question. To understand the assembly of these complex communities, the Lieberman Lab reconstructs the recent on-person evolution of strains on […]
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Frontiers in Genomics: Alicia Martin
Genomics for the world: ancestral diversity enhances genomic discovery, resolution, interpretation, and contextualization
Frontiers in Genomics: Alicia Martin
Genomics for the world: ancestral diversity enhances genomic discovery, resolution, interpretation, and contextualization
Resumen de la plática Genomic studies are transforming precision medicine, yet their benefits often overlook diverse, underserved populations. Our research shows that embracing ancestral diversity not only addresses this ethical concern but also enhances genomic discovery, resolution, interpretation, and contextualization. Analyzing lung diseases across multiple biobanks, we found consistent genetic effects and improved our understanding […]
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Frontiers in Genomics: Birte Hocker
Protein Design 2.0
Frontiers in Genomics: Birte Hocker
Protein Design 2.0
Resumen de la plática Proteins are the machines of life. These diverse macromolecules are essential for all cellular processes. Nature has generated an impressive set of proteins through evolution. Many of its structures and even more sequences are known by now. This enormous amount of data can be leveraged for protein design. The design of […]