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Frontiers in Genomics: Birte Hocker
Protein Design 2.0
Frontiers in Genomics: Birte Hocker
Protein Design 2.0
Resumen de la plática Proteins are the machines of life. These diverse macromolecules are essential for all cellular processes. Nature has generated an impressive set of proteins through evolution. Many of its structures and even more sequences are known by now. This enormous amount of data can be leveraged for protein design. The design of […]
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Frontiers in Genomics: Alfredo Hidalgo
Tecnologías de secuenciación masiva y su impacto en la investigación y el manejo clínico del cáncer
Frontiers in Genomics: Alfredo Hidalgo
Tecnologías de secuenciación masiva y su impacto en la investigación y el manejo clínico del cáncer
Resumen de la plática El cáncer surge debido a la acumulación de alteraciones en el genoma de las células. Estas alteraciones pueden ir desde mutaciones puntuales hasta pérdida y ganancia de cromosomas completos. La caracterización de estas alteraciones en el genoma de las células neoplásicas a través de la aplicación de metodologías de análisis genómico […]
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Frontiers in Genomics: Mayra Furlan
RNA molecules promote RNA Polymerase II pausing in erythrocytes
Frontiers in Genomics: Mayra Furlan
RNA molecules promote RNA Polymerase II pausing in erythrocytes
AVISO: por solicitud de la ponente, este seminario no se transmitirá por YouTube. Resumen de la plática Erythrocytes are specialized cells that carry haemoglobin throughout the bloodstream in all vertebrates. Obtention of mature erythrocytes involves genome-wide chromatin compaction, gain of heterochromatin, and gene silencing, making the erythroid genome a unique scenario to investigate chromatin architecture […]
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Frontiers in Genomics: Shushkov Philip
Computational inference and integration in single-cell transcriptomics
Frontiers in Genomics: Shushkov Philip
Computational inference and integration in single-cell transcriptomics
Resumen de la plática Understanding the transcriptional dynamics at the single-cell level is a central challenge in deciphering developmental processes. Current sequencing technologies allow the measurement of the transcription profiles of hundreds of thousands of individual cells. However, integration of multiple single-cell transcriptomic datasets and inference of developmental progressions of cells is hampered by sampling […]
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