Sriram Chandrasekaran, Assistant Professor, Biomedical Engineering, University of Michigan, Ann Arbor Seminar abstract: By 2050, we may lose 10 million people a year to drug-resistant infections. Unfortunately, the pace of drug discovery has not kept up with the rapid emergence of these pathogens. Drug combinations have great potential to reduce the spread of drug-resistant bacteria. […]

Judy Lieberman, Chair in Cellular and Molecular Medicine, Program in Cellular and Molecular Medicine, Boston Children's Hospital; Professor of Pediatrics, Harvard Medical School https://www.mcb.harvard.edu/directory/judy-lieberman/ https://www.dfhcc.harvard.edu/insider/member-detail/member/judy-lieberman-md-phd/ Frontiers in Genomics

William Harcombe, University of Minnesota Predicting eco-evolutionary dynamics is vital to our ability to understand and manage critical microbial communities. Using computational models and experimental systems we have found that metabolic mechanisms provide a basis for quantitatively predicting the dynamics of microbial systems. We have found that when microbes cross-feed, obtaining metabolites from one another, […]

Summary: In this seminar I will provide an overview of the evidence for using pharmacogenomics to guide prescribing, present clinical situations where pharmacogenomics could be useful, and describe key considerations for using pharmacogenomics in practice. Chad Bousman, Associate Professor, Departments of Medical Genetics, Psychiatry, Physiology & Pharmacology, and Community Health Sciences, University of Calgary https://profiles.ucalgary.ca/chad-bousman Frontiers in […]

Decoding Root Growth to Mitigate Climate Change Climate change will soon profoundly and negatively affect the vast majority of our planet’s biota, including most human beings. Despite the importance and urgency of addressing this problem, we still lack technologies to globally address the root cause of climate change – increased levels of CO2 in the […]

Raquel Cuevas-Díaz Durán, School of Medicine and Health Sciences, ITESM https://research.tec.mx/vivo-tec/display/PID_66289 Resumen de la ponencia The nervous system of multicellular organisms comprises highly specialized cells which perform distinct physiological functions. Even though they possess nearly identical genomic DNA, their spatio-temporal heterogeneity is achieved through epigenetic mechanisms, for example DNA methylation, histone post-transcriptional modifications, chromatin remodeling, […]

Resumen de la ponencia High throughput genomic methods, such as ChIP-Seq, have greatly expanded our knowledge of transcription factor (TF) binding to DNA. A frequent observation is the presence of binding sites for individual TFs that span a wide range of apparent affinities. A quantitative biophysical understanding of the basis of TF binding strength is […]

Tony Hunter, American Cancer Society Professor, Molecular and Cell Biology Laboratory, Renato Dulbecco Chair, Salk Institute Resumen de la ponencia I will discuss our recent studies on protein histidine phosphorylation and its function as a reversible posttranslational modification. I will describe how we developed monoclonal antibodies specific for the 1-pHis and 3-pHis isoforms, and have […]

Juan Francisco Jiménez Bremont, Profesor-Investigador Titular C (SNI 3), Division de Biología Molecular, Instituto Potosino de Investigación Científica y Tecnológica (IPICyT) Resumen de la ponencia Nuestro grupo de investigación se ha enfocado en la caracterización molecular y funcional de genes involucrados en la respuesta al estrés de plantas. Inicialmente mediante bibliotecas cDNA construidas en frijol, […]

Alejandro Sánchez Alvarado, Stowers Institute for Medical Research https://www.stowers.org/labs/sanchez-alvarado-lab https://youtube.com/live/8YaefxZtNxI?feature=share Frontiers in Genomics