Frontiers in Genomics: James Galagan
A neural network for quantitative biophysical transcription factor binding site design
Auditorio "Dr. Guillermo Soberón" del CCG
Centro de Ciencias Genómicas UNAM Morelos, Cuernavaca, Morelos, Mexico
Resumen de la ponencia High throughput genomic methods, such as ChIP-Seq, have greatly expanded our knowledge of transcription factor (TF) binding to DNA. A frequent observation is the presence of binding sites for individual TFs that span a wide range of apparent affinities. A quantitative biophysical understanding of the basis of TF binding strength is […]