Abstract My laboratory has long been fascinated by phenazines, a class of secreted redox-active metabolites produced by diverse soil bacteria, including the opportunistic human pathogen Pseudomonas aeruginosa. Though phenazines were once thought to function primarily as antibiotics to kill competitors, we have found additional physiological functions for phenazines under anoxic conditions, including roles in signaling, […]

Abstract Plants interact with a huge diversity of microorganisms in associations ranging from parasitic to mutualistic, with either bacteria or filamentous fungi or oomycetes. Since plants colonized lands 450 million years ago, these associations have evolved in opposite directions. Mutualism has been maintained for hundreds of million years whereas the interactions with parasites are fast […]

Aviso: el seminario de la Dra. Venturelli programado para el 17 de octubre se canceló por causas ajenas a la LCG. Ophelia Venturelli. Departments of Biochemistry, Chemical & Biological Engineering, Bacteriology. University of Wisconsin-Madison https://www.venturellilab.org/ Frontiers in Genomics

Abstract: DNA methyltransferase 1 (DNMT1) is critical during early development. Absence of DNMT1 is embryonic lethal and insufficient DNMT1 activity can lead to disorganized cell differentiation, increased cell death of specialized cells and implantation failure. DNMT1 is known for catalyzing DNA methylation maintenance, notably at imprinting control regions (ICR). However, evidence supports DNMT1 functionality beyond […]

Aviso: el seminario del Dr. Drukker programado para el 31 de octubre se canceló por causas ajenas a la LCG. Micha Drukker, Professor Stem Cells, Developmental Biology, and Immunology. Leiden Academic Centre for Drug Research (LACDR) / Leiden University https://www.universiteitleiden.nl/en/staffmembers/micha-drukker#tab-1 Frontiers in Genomics